Cardarine (GW501516)

Intro

Cardarine (GW501516) is a fascinating drug, no longer in development, that most people do not even know exists.  A much greater following happens to be in the fitness world, where word of mouth spreads quickly by braggarts and coach-to-player relationships.  Bottom line is that if you aren’t using this drug in fitness you will be falling behind your peers in all sports, especially any activity that involves endurance.  Even those who are not in the fitness world can benefit from the fat loss advantages too.  In this expose, I will separate facts from the many fictions on Cardarine (GW501516).

cardarine (GW 501516) review

The past and present

Cardarine (GW-501516) was in development during the 90’s and 2000’s by GlaxoSmithKline and Ligand, which are 2 pharmaceutical companies.  Their original intent was to research a drug that would reverse tumor growth.  What they found during the first trials was a drug that helped reverse poor heart health.  The next trials found it helped with obesity and type 2 diabetes.

…suggest that activation of PPARs may cause the body to increase its use of fatty acids for energy, and lead to a reduction in body fat. There are also data to suggest a role for PPARs in regulating lipid (e.g., cholesterol) levels and inflammation

During the 2000’s word started leaking about this miracle drug that you could take and get a boost in endurance in whatever particular sport or skill you chose.  Coaches tried their best to keep Cardarine (GW 501516) a secret for as long as they could, but athletes like to talk and gossip too much.

During the 2008 China Olympics, it was estimated that most competitors were using it in all kinds of things including running/track, basketball, cycling, swimming, soccer, boxing, weightlifting and more.   The next year, they banned Cardarine (GW501516) from competition, and every other sports federation followed suit.  Now those caught using it will face suspensions for doping.

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How it works for endurance

If you go outside right now and sprint for 3 minutes straight as fast as you can you will notice afterward you become very winded and will huff and puff.  This is because your heart rate is like the car engine RPM’s where they rev up until you cannot go anymore.

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Cardarine (GW-501516) binds to the PPAR (Peroxisome proliferator-activated receptor beta) agonist receptors.  Energy output is thus changed, as the activity in the genes gets turned around.  While the drug is active in your system, you will receive a strong rise in endurance and will notice you are able to push yourself more without becoming out of breath.  Essentially your car engine is not revving up as hard as before, so you aren’t so winded.  The end result is your race times improve, and you can do a lot more long distance cardio without tiring yourself out, and this will benefit you in every type of sport out there.  Now you see why so many Olympians used this stuff back in 2008!

How it works for fat loss

Cardarine (GW 501516) can be used by those who are already lean or those who are obese in both genders.  It increases glucose uptake by changing how the body treats nutrients, drastically reducing how fat is stored.  This translates to a lowering of body fat whether the person alters their diet or not, although in studies those that did eat better had much more pronounced results.

cardarine (GW-501516) results

To determine whether GW501516 regulates fatty acid combustion, a FAO assay was performed, revealing that GW501516 induced oleate oxidation approximately 7-fold (P<0.001) compared with vehicle. We routinely checked that the HSKM cells remained viable throughout the studies and that cell toxicity did not occur. No reduction in cell viability was noted.

Other benefits

Another amazing thing Cardarine (GW-501516) does is improve cholesterol levels and reverses type 2 diabetes.  Again in both cases, studies showed results were much better when the person altered their diet lifestyle and exercised more.

Side effects

Cardarine (GW 501516) is nonhormonal, not suppressive, safe for males and females, and safe no matter what kind of shape you are in. A study in Australia was done where men took the drug for 6 months and there were no side effects reported.  There are many athletes who have used the drug for years with no adverse issues reported, although I do recommend you cycle off the drug every 3 months to give the body a break.

This study elucidates the mechanism of action of this PPARδ agonist on lipoprotein metabolism and supports its potential use in treating dyslipidemia in obesity. All these results were achieved without any significant alteration in body weight or insulin resistance. No adverse events were observed

Popular stacks

Solo

Cardarine (GW-501516) can be used by itself at 10-20mgs a day.  It also can be added at a dosage of 10-20mgs a day to both anabolic steroid stacks and SARM’s stack.

Anabolic Steroids

Stacking it with the harshest anabolic steroids (especially Trenbolone) is a wise choice. Since it helps offset the negative endurance issues.  It also will help with your lipid health too.

Others like to stack it in with cutting cycles such as Winstrol, Turinabol, Anavar, Masteron. Or trenbolone to increase fat loss without adding to side effects.

Other SARMs

If you want to avoid anabolic steroids, and choose to run a mild fat burning stack. You can use it with RAD140 Testolone or S4 Andarine for fat loss.  It also stacks well with other compounds like Ligandrol LGD4033-Anabolicum and MK2866 Ostarine Ostabolic for both fat loss and endurance benefits.

Using during post cycle therapy

Many guys and gals are turning to Cardarine (GW-501516) during their post cycle therapy. To help avoid what is called ‘fat rebound‘ after coming off of a cycle. Also, people tend to have a drop in workout effectiveness and endurance as a cycle comes to an end. In this case this drug will help with bigtime.

Half-life and detection times

The half-life is around 24 hours, so once a day dosing is perfectly fine.  Some users like to take it about 3 hours before their exercise.

Detection times are unknown but the consensus seems to be around 3-4 weeks.   Cheating, however, is wrong. So, if you are a tested athlete I do not endorse using Cardarine (GW 501516). Because it is unfair to your peers who aren’t using it.

Where to buy Cardarine

It is important to know that most Cardarine (GW501516) out there is fake.  We are seeing a lot of companies lace their products with clenbuterol, ephedra, and even caffeine to fool consumers into thinking it is working.   Over the past 2 years, credit card merchants and auction-based websites like Amazon and eBay have banned the sale of the drug. Therefore, it has become harder to find the legitimate product.

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Luckily SARMS1 and eSARMS still sells real Cardarine-(GW501516).  I would not trust any other company.  For more information on where to find this drug please go to our forums at elitefitness.com and evolutionary.org.

Cardarine Review
  • Lean Muscle Mass Gains
  • Fat Loss
  • Strength Gains
  • Boost Endurance
4.8

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